Essential Design Output(s) and Design transfer

Hi all
At my firm we are looking in to optimizing how we determine the essential design outputs which should be design transferred and be subject for process validation and continuous monitoring in production.
We have a good Design input/output treceability matrix but we always struggling how to determine which of these outputs should be design transferred as "Essential". I mean the outputs consists of e.g many drawings with a lot of specifications but not all of these specifications are essential meaning that not all specifications should be subject for process validation etc.
The next thing is how to document these "essential" specifications - in a separate document, column in the matrix or other?
How do you handled this process in your systems?

All input are appreciated - thank you

You need to consult with the several specialists to do that and provide an plan of your building and desired works

I think that in this case, it is not necessary to rely on the output data. Although, of course, it never hurts to check your work for errors in various ways. Especially when it comes to equipment or an important project.
However, it seems to me that you should contact the developer of the program in which you work directly. My friend participated in the shopping center project. As a result, it turned out luxurious amenities and beautiful interiors. And all this is because he was well versed in the programs in which he worked.
Perhaps you should tighten up these skills.